Search our team at AdventHealth Research Institute
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NCT03324841
Caris Molecular Intelligence and Caris Centers of Excellence for Precision Medicine Network Outcomes Associated Repository
This study is not currently enrolling.Research Area: Clinical Cancer ResearchThe purpose of the research repository is to collect information, which will be used for research studies to evaluate how clinical outcomes relate to Caris Molecular INtelligence Services.
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NCT03295734
ACES: Ace Inhibitors Combined with Exercise for Hypertensive Seniors
This study is not currently enrolling.Associated Conditions: Aging-Nutrition and Physical ActivityResearch Area: Translational ResearchResearch Location: Orlando, FloridaThe purpose of this research study is to see if regular exercise when combined with one of three commonly used high blood pressure medications can improve the physical abilities of older adults to...
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NCT04168580
BATSR: BAT as a therapeutic for the metabolic and cardiac dysfunction with senescence
This study is not currently enrolling.Associated Conditions: ExerciseResearch Area: Translational ResearchTo be enrolled in this study, you must meet certain requirements. You may be eligible to participate if you meet the following criteria:
BMI ≤35 kg/m2
65-90 years of ageStudy Duration: Up to 120...
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NCT03213704
NCI-COG Pediatric Match (Molecular Analysis for Therapy Choice) - Phase 2 Subprotocol of LOXO-101 (Larotrectinib) in Patients with Tumors Harboring Actionable NTRK Fusions
This study is not currently enrolling.Associated Conditions: Cancer, Companion StudyResearch Area: Clinical Cancer ResearchResearch Location: Orlando, FloridaThe overall goal of this study is to test any good and bad effects of the study drug LOXO-101 (larotrectinib) on your tumor.
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NCT04164966
HONEY: Development of novel biomarkers for the early diagnosis of type 1 diabetes
This study is not currently enrolling.Associated Conditions: Diabetes-MechanismsResearch Area: Translational ResearchResearch Location: Orlando, FloridaType 1 Diabetes (T1D) or Juvenile diabetes is an autoimmune disease projected to affect 5 million people, including 600,000 children in US alone, by the year 2050. There is currently no cure or...
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NCT04057677
RECOVER: Exercise training as an intervention to improve muscle function and Recovery following bed rest in older adults with type 2 diabetes
This study is not currently enrolling.Associated Conditions: Diabetes-Nutrition and Physical ActivityResearch Area: Translational ResearchThe purpose of this research is to gather data on how exercise can help recovery of muscle mass, strength, and physical function after bedrest. Procedures for this study include gathering medical...
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NCT04034706
EPIC: Transcriptomic and epigenetic characterization of the subcutaneous fat depots in PCOS women
This study is not currently enrolling.Associated Conditions: Polycystic Ovary SyndromeResearch Area: Translational ResearchPolycystic ovary syndrome, or PCOS, is a hormonal condition where your reproductive hormones are out of balance. PCOS is also associated with an increased risk to become obese and a male-like fat...
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NCT03233711
A Randomized Phase II Study of Nivolumab after Combined Modality Therapy (CMT) in High Risk Anal Cancer
This study is not currently enrolling.Associated Conditions: Anal CancerResearch Area: Clinical Cancer ResearchResearch Location: Orlando, FloridaThe purpose of this study is to find if adding the study drug, nivolumab (also known as OPDIVO), after standard chemotherapy {(mitomycin-C and 5-fluorouracil 5(-RU) or capecitabine) or 5-FU and...
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NCT03856099
A Multicenter, Open-Label, Phase Ⅱ Clinical Trial to Evaluate the Safety and Efficacy of TTAC-0001, a Fully Human Monoclonal Antibody in Patients with Recurrent Glioblastoma Progressed on Bevacizumab Including Therapy
This study is not currently enrolling.Associated Conditions: Brain CancerResearch Area: Clinical Cancer ResearchThe aim of this study is to assess the safety and effectiveness of the study drug, TTAC-0001 to patients with recurrent glioblastoma which has progressed on bevacizumab treatment. Another aim is to...
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NCT03126916
A Phase 3 Study of 131I-Metaiodobenzylguanidine (131I-MIBG) or Crizotinib Added to Intensive Therapy for Children with Newly Diagnosed High-Risk Neuroblastoma
This study is not currently enrolling.Associated Conditions: Brain CancerResearch Area: Clinical Cancer ResearchThe overall goals of this study are to: Compare the effects, good and/or bad, of the experimental drug 131I-MIBG added to current COG recommended therapy to the effects of current COG recommended...
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NCT03960827
MoTrPAC: Molecular Transducers of Physical Activity Consortium
This study is not currently enrolling.Associated Conditions: ExerciseResearch Area: Translational ResearchResearch Location: Orlando, FloridaThe goal of the Molecular Transducers of Physical Activity Consortium (MoTrPAC) is to assess molecular changes that occur in response to physical activity (PA). To achieve this aim, a mechanistic...
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MATPET: Dynamic PET imaging in skeletal muscle and adipose tissue to explore mechanisms of peripheral glucose uptake in African American, Hispanic, and Caucasian Women
This study is not currently enrolling.Associated Conditions: Diabetes-MechanismsResearch Area: Translational ResearchStudy Purpose: The objective of this study is to obtain a better understanding between skeletal muscle characteristics and the ability to metabolize glucose. AdventHealth is seeking African American...