Search our team at AdventHealth Research Institute
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NCT04811092
HYPERION A Phase 3, Randomized, Doubleblind, Placebo-controlled Study to Evaluate Sotatercept When Added to Background Pulmonary Arterial Hypertension (PAH) Therapy in Newly Diagnosed Intermediate-and High-risk PAH Patients
This study is not currently enrolling.Associated Conditions: Pulmonary HypertensionResearch Area: Heart, Lung and Vascular ResearchResearch Location: Orlando, FloridaPulmonary arterial hypertension (PAH) is a disease affecting the blood vessels of the lungs. PAH leads to increased pressure in the blood vessels of the lungs which further leads to straining of the...
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NCT04089358
StepByStep: A Randomized Trial of a Mobile Health and Social Media Physical Activity Intervention among Adolescent and Young Adult Childhood Cancer Survivors
This study is not currently enrolling.Associated Conditions: Pediatric CancerResearch Area: Clinical Cancer ResearchResearch Location: Orlando, FloridaThe overall goals of this study are: (1) To compare the effect of 2 different physical activity programs on physical activity levels in adolescents and young adults who received and completed...
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NAD-flux: Measurement of NAD+ Synthesis in Human Skeletal Muscle
This study is not currently enrolling.Associated Conditions: WellnessResearch Area: Translational ResearchResearch Location: Orlando, FloridaNicotinamide adenine dinucleotide (NAD) is a vitally important substance that is found in all cells of the body. Elevated levels of NAD are linked to health and well-being. The key objective of this...
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NCT04360096
Inhaled RLF-100 for the Treatment of Severe COVID-19 without respiratory failure
This study is not currently enrolling.Associated Conditions: COVIDResearch Area: Critical Care ResearchThe purpose of this research is to: To show whether the study drug RLF-100 along with standard of care is better than standard of care alone in preventing progression from Severe COVID-19 to Critical...
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NCT04805970
RECODE: Researching Covid Outcomes in Diabetes
This study is not currently enrolling.Research Area: Translational ResearchResearch Location: Orlando, FloridaWe invite you to take part in a research study because you have previously had a confirmed diagnosis for COVID-19 (the new coronavirus) disease. You have recovered, or are recovering from this disease...
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NCT04722354
ABA: ABA-Abscisic Acid Effects on Glucose Homeostasis and Insulin Sensitivity
This study is not currently enrolling.Associated Conditions: Diabetes-Drug StudyResearch Area: Translational ResearchThe purpose of this study is to determine the effects of oral abscisic acid (ABA) on glucose metabolism in subjects with defined prediabetes.
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NCT04625270
A Phase 2 Study of VS-6766 (Dual RAF/MEK Inhibitor) Alone and In Combination with Defactinib (FAK Inhibitor) in Recurrent Low-Grade Serous Ovarian Cancer (LGSOC).
This study is not currently enrolling.Associated Conditions: Ovarian, Fallopian, or Primary Peritoneum CancerResearch Area: Clinical Cancer ResearchResearch Location: Orlando, FloridaThe main aims of this clinical study are to: (a) Find out if the best course of study treatment is to take either VS-6766 alone (monotherapy) or to take VS-6766 together (in combination) with...
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Mother Providing Recorded Voice to Her Preterm Infant in Incubator Improves Her Own Grief and Emotional Status
This study is not currently enrolling.Associated Conditions: NeonatalResearch Area: Pediatric Research and Clinical TrialsResearch Location: Orlando, FloridaStudies have shown that infants prefer the sound of their mother's voice above all others. After 2 weeks (or 14 days) of life, we would like to begin playing a recording to babies of their mother's...
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GluCog: Glycemic Variability and Fluctuations in Cognitive Status in Adults with Type I Diabetes
This study is not currently enrolling.Associated Conditions: Diabetes-MechanismsResearch Area: Translational ResearchThe purposes of this study is to understand how thinking, emotions, and blood glucose fluctuate over hours and days in people with type I diabetes.
Study Commitment: 1 Month
Aged ≥ 18 years
Sex: Male... -
NCT03926130
A Phase 3, Multicenter, Randomized, Double-Blind, Placebo- and Active-Controlled, Treat-Through Study to Evaluate the Efficacy and Safety of Mirikizumab in Patients with Moderately to Severely Active Crohn's Disease.
This study is not currently enrolling.Associated Conditions: Inflammatory Bowel Disease (IBD)Research Area: Digestive Health and SurgeryThe main reason for you to take part in this study is not to treat you for your condition but to help in answering the following research questions:
How safe mirikizumab is and whether you might have... -
NCT04502316
BAROSTIM THERAPY in Heart Failure with Reduced Ejection Fraction A Post-Market Registry with the BAROSTIM NEO System
This study is not currently enrolling.Associated Conditions: Heart FailureResearch Area: Heart, Lung and Vascular ResearchResearch Location: Orlando, FloridaYou are invited to participate in a Registry to track the performance of the BAROSTIM NEO Device. You are being invited because you have been implanted with the Device because of your condition called...
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NCT04538261
Elevation of the Fetal Buttocks Prior to External Cephalic Version
This study is not currently enrolling.Associated Conditions: Neonatal, Care DeliveryResearch Area: Pediatric Research and Clinical TrialsIn this study, we will analyze the available NICU data to determine the predictive value of a Bronchopulmonary Dysplasia (BPD) scoring system. Later, we will determine a threshold score at which an...