Search our team at AdventHealth Research Institute
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NCT05083481
A Phase 1/2 Study of ASP1570 as Monotherapy and in Combination With Pembrolizumab or Standard Therapies Including Chemotherapy and/or Immunotherapy in Participants With Locally Advanced or Metastatic Solid Tumors
This study is not currently enrolling.Research Area: Clinical Cancer Research -
A Phase 1b/2a, Multicenter, Open-Label Study of Pocenbrodib as Monotherapy and in combination With Abiraterone Acetate, Olaparib, or 177Lu-PSMA-617 in Participants with Metastatic Castration-Resistant Prostate Cancer (mCRPC)
This study is not currently enrolling.Associated Conditions: Prostate CancerResearch Area: Clinical Cancer Research -
NCT05155332
Phase I open-label, dose escalation trial of BI 1831169 monotherapy and in combination with ezabenlimab in patients with advanced or metastatic solid tumors.
This study is not currently enrolling.Research Area: Clinical Cancer Research -
NCT06819007
A Phase 3, Open-label, Multicenter, Randomized Trial of Trastuzumab Deruxtecan with Bevacizumab Versus Bevacizumab Monotherapy as First-line Maintenance Therapy in HER2-Expressing Ovarian Cancer” GOG 3112/ DSI-T-DXd ENHERTU (DO-01); DESTINY-Ovarian01 (DO-01)] DS8201-772
This study is not currently enrolling.Associated Conditions: Ovarian, Fallopian, or Primary Peritoneum CancerResearch Area: Clinical Cancer ResearchResearch Location: Orlando, FloridaThis study consists of two parts: Part 1 (safety run-in) and Part 2 (randomized part [like the flip of a coin]). The purpose of Part 1 is to learn more about the safety and tolerability of the...
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NCT05929235
A Phase 1, First-in-Human, Dose-Escalation and Expansion Study of FX-909 in Patients With Advanced Solid Malignancies, Including Advanced Urothelial Carcinoma
This study is not currently enrolling.Associated Conditions: Multiple Tumor TypesResearch Area: Clinical Cancer ResearchResearch Location: Celebration, Florida -
NCT03142152
Assessment of the Carillon Mitral Contour System® in Treating Heart Failure with Functional Mitral Regurgitation
This study is not currently enrolling.Research Area: Heart, Lung and Vascular ResearchResearch Location: Tampa, FloridaThe purpose of this clinical study is to evaluate the safety and effectiveness of the Carillon Mitral Contour System in people who have mitral regurgitation resulting from heart failure.
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NCT06639958
Risk-Based 6MP Adherence Enhancement Strategies in Children, Adolescent and Young Adults With ALL - A Pilot Study Study Sponsor: Children’s Oncology Group
This study is not currently enrolling.Research Area: Pediatric Research and Clinical TrialsResearch Location: Orlando, FloridaThis study is being done to answer the following question: Can we help children, adolescents and young adults with ALL to remember to take their daily Maintenance medicine, 6MP, at home? We are doing...
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NCT06616974
A Phase 2, Double-blind, Randomized, Placebo-Controlled Study to Assess the Efficacy and Safety of TX000045 After 24 Weeks of Treatment in Patients With Pulmonary Hypertension Secondary to Heart Failure With Preserved Ejection Fraction (PH-HFpEF)
This study is not currently enrolling.Research Area: Heart, Lung and Vascular ResearchThe study Sponsor is developing the investigational (experimental) drug TX000045 as a potential new treatment for patients with high lung blood pressure due to heart failure.
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NCT05514717
A Phase 1, First-in-Human, Dose Escalation and Expansion, Multicenter Study of XMT-2056 in Participants with Advanced/Recurrent Solid Tumors that Express HER2
This study is not currently enrolling.Associated Conditions: Metastatic Solid TumorsResearch Area: Clinical Cancer ResearchResearch Location: Celebration, FloridaThe purpose of the study is to: During the Dose Escalation part, find the most tolerated dose of the Study Drug that may provide potential benefit. During the Enrichment and Expansion parts, further...
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Discovery and Characterization of Genetic Risk Loci in Sjögren’s Syndrome
This study is not currently enrolling.Research Area: Pediatric Research and Clinical TrialsResearch Location: Orlando, Florida -
NCT06676072
Safety and effectiveness of the TactiFlex SE Catheter and Volt Pulsed Field Ablation (PFA) Generator in subjects with paroxysmal atrial fibrillation
This study is not currently enrolling.Research Area: Heart, Lung and Vascular ResearchResearch Location: Orlando, FloridaThe purpose of the study is to find out if the investigational TactiFlex PFA System, the device that is being studied, is safe and effective in treating adults like you who have atrial fibrillation
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NCT06400342
The REVIVE-TAVR (Randomized Evaluation of Valve-In-Valve versus Explantation for failed Transcatheter Aortic Valve Replacement)
This study is not currently enrolling.Research Area: Heart, Lung and Vascular Research