Search our team at AdventHealth Research Institute
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NCT03959085
A Phase 3 Randomized Trial of INotuzumab Ozogamicin (IND#: 133494, NSC#: 772518) for Newly Diagnosed High-Risk B-ALL; Risk-Adapted Post-Induction Therapy for High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and Disseminated B-LLy
This study is currently enrolling.Associated Conditions: LeukemiaResearch Area: Clinical Cancer ResearchDisseminated B-Cell Lymphoblastic Lymphoma (B-LLy): The overall goal of this study is to determine the outcomes of subjects with disseminated B-LLy receiving High Risk B-cell Acute Lymphoblastic...
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NCT02981628
A Phase 2 Study of INotuzumab Ozogamicin (NSC# 772518, IND #133494) in Children and Young Adults with Relapsed or Refractory CD22+ B-Acute Lymphoblastic Leukemia (B-ALL)
This study is currently enrolling.Associated Conditions: LeukemiaResearch Area: Clinical Cancer ResearchResearch Location: Orlando, FloridaThe overall goal of this study is to find out what effect, good and/or bad, the drug inotuzumab ozogamicin has on children and young adults with relapsed or refractory B-ALL.
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NCT03067181
A Phase 3 Study of Active Surveillance for Low Risk and a Randomized Trial of Carboplatin vs. Cisplatin for Standard Risk Pediatric and Adult Patients with Germ Cell Tumors
This study is currently enrolling.Associated Conditions: Brain CancerResearch Area: Pediatric Research and Clinical TrialsResearch Location: Orlando, FloridaLow Risk Subjects (Age <50 Years): The overall goal is to see if monitoring subjects with low risk germ cell tumors after their tumor is removed is as effective as following surgery with chemotherapy...
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NCT04071327
PHAR - Pulmonary Hypertension Association Registry
This study is currently enrolling.Associated Conditions: Pulmonary HypertensionResearch Area: Heart, Lung and Vascular ResearchResearch Location: Orlando, FloridaWe are asking you to be included in the Pulmonary Hypertension Association (PHA) Registry (PHAR). This is a national project about people who have pulmonary hypertension (PH). We are asking you to...
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NCT03962543
A Phase 2b Trial of the MEK 1/2 Inhibitor (MEKi) PD-0325901 in Adult and Pediatric Patients with Neurofibromatosis Type 1 (NF1)-Associated Inoperable Plexiform Neurofibromas (PNs) that are Progressing or Causing Significant Morbidity
This study is currently enrolling.Associated Conditions: NeurofibromatosisResearch Area: Pediatric Research and Clinical TrialsResearch Location: Orlando, FloridaThis research is conducted to study an investigational drug referred to as PD-0325901 (also known as mirdametinib) that has not been approved by the US Food and Drug Administration (FDA) or any other...
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NCT00097292
TRIALNET: Natural History Study of the Development of Type 1 Diabetes
This study is currently enrolling.Associated Conditions: Diabetes-MechanismsResearch Area: Translational ResearchResearch Location: Orlando, FloridaYou are being asked to be in a research study called the TrialNet Natural History Study of the Development of Type 1 Diabetes. As you know, TrialNet is an international research group dedicated to the...
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NCT02402244
The Project: EveryChild Protocol: A Registry, Eligibility Screening, Biology and Outcome Study
This study is currently enrolling.Associated Conditions: Multiple Tumor TypesResearch Area: Clinical Cancer ResearchResearch Location: Orlando, FloridaWe are doing this study to find better ways to diagnose, treat and prevent cancers in children, adolescents and young adults. To do this, we need to learn more about cancers that happen to children...
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Transoral Surgery Registry (TOS Registry)
This study is currently enrolling.Associated Conditions: Head and Neck CancerResearch Area: Surgical ResearchA research registry is a database (data warehouse) where clinical and other related information from patients is collected and stored for medical research. The purpose of this TOS registry is to...
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NCT01515787
A Phase II/III of Neoadjuvant FOLFOX with Selective Use of Combined Modality Chemoradiation versus Preoperative Combined Modality Chemoradiation for Locally Advanced Rectal Cancer Patients Undergoing Low Anterior Resection with Total Mesorectal Excision (PROSPECT)
This study is currently enrolling.Associated Conditions: Colorectal CancerResearch Area: Clinical Cancer ResearchResearch Location: Orlando, Florida[$] [Abbreviated - Closed] The purpose of this study is to compare the effects, both good and bad, of the standard treatment of chemotherapy and radiation to chemotherapy using a combination regimen...
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NCT03334292
Natural History of Wilson Disease: Registry for Patients with Wilson Disease
This study is currently enrolling.Associated Conditions: Wilson’s DiseaseResearch Area: Pediatric Research and Clinical TrialsResearch Location: Orlando, FloridaYou are invited to donate your blood, urine, research data, and related information to be stored (banked) in a research specimen/data database or bank where it can be used for future research projects...
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North American Pediatric Renal Trials Collaborative Studies (NAPRTCS)
This study is currently enrolling.Associated Conditions: TransplantResearch Area: Pediatric Research and Clinical TrialsResearch Location: Orlando, FloridaNAPRTCS is a research effort that was organized in 1987 by a group of physicians and surgeons committed to the success of pediatric renal transplant.
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Correlation of Intraoperative Drop Test to Postoperative Range of Motion in Total Knee Arthroplasty
This study is currently enrolling.Research Area: Orthopedic ResearchThe purpose of this study is to investigate the correlation between perioperative drop leg test and the final range of motion in primary total knee arthroplasty procedures.