Search our team at AdventHealth Research Institute
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NCT05348785
A Phase 2b, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Determine the Efficacy and Safety of BIIB122 in Participants with Parkinson’s Disease
This study is currently enrolling.Associated Conditions: ParkinsonsResearch Area: Neuroscience ResearchResearch Location: Orlando, FloridaYou may be eligible to take part in the study because you have Parkinson’s Disease (PD). Only people who have been diagnosed with PD in the past 2 years and who are within the ages of 30 to 80 years...
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NCT05064709
Assessment of Implantable CCM in the Heart Failure Group with Higher Ejection Fraction
This study is currently enrolling.Associated Conditions: Heart FailureResearch Area: Heart, Lung and Vascular ResearchResearch Location: Orlando, FloridaYour doctor has diagnosed you with HF. You are being asked to consider voluntary participation in a research study of CCM treatment with the Optimizer System, sponsored by Impulse Dynamics (USA) Inc...
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NCT04245397
A Phase 1, Open-Label, Dose-Escalation with Expansion Study of SX-682 in Subjects with Myelodysplastic Syndrome Who Had Disease Progression or are Intolerant to Prior Therapy
This study is currently enrolling.Associated Conditions: Myelodysplastic SyndromeResearch Area: Clinical Cancer ResearchResearch Location: Orlando, FloridaThis research study is studying an investigational immunotherapy called SX-682 as a possible treatment for Myelodysplastic Syndrome.
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NCT04321031
STARZL NETWORK FOR EXCELLENCE IN PEDIATRIC TRANSPLANTATION (snept) to improve the health of pediatric LIVER TRANSPLANT PATIENTS
This study is currently enrolling.Associated Conditions: Liver DiseaseResearch Area: Pediatric Research and Clinical TrialsResearch Location: Orlando, FloridaPediatric liver transplantation has become the standard of care for many children with liver diseases. However, different institutions often treat and manage children with liver transplant in...
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NCT05197920
DREAM: Diabetes RElated to Acute pancreatitis and its Mechanisms (DREAM). An observational cohort study from the Type 1 Diabetes in Acute Pancreatitis Consortium (T1DAPC)
This study is currently enrolling.Associated Conditions: Diabetes-Drug StudyResearch Area: Translational ResearchResearch Location: Orlando, FloridaStudy Purpose: The purpose of this research study is to find out how many people with acute pancreatitis develop diabetes. Risk factors for diabetes and the types of diabetes that occur after acute...
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NCT04796337
SOTERIA - An Open-Label Long-Term Follow-Up Study to Evaluate the Effects of Sotatercept when Added to Background Pulmonary Arterial Hypertension (PAH) Therapy for the Treatment of PAH
This study is currently enrolling.Associated Conditions: Pulmonary HypertensionResearch Area: Heart, Lung and Vascular ResearchResearch Location: Orlando, FloridaWe are asking you to take part in this study because you are currently in a study with sotatercept and we want to find out if continuing to take sotatercept is safe and effective over a long period of...
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NCT04226547
CATALYST - Clinical trial of atrial fibrillation patients comparing left atrial appendage occlusion therapy to non-vitamin K antagonist oral anticoagulants
This study is currently enrolling.Associated Conditions: CoagulationResearch Area: Heart, Lung and Vascular ResearchResearch Location: Orlando, FloridaThe purpose of this research study is to compare the safety and effectiveness of the Amulet device compared to non-vitamin K antagonist oral anticoagulants (NOACs) for ischemic stroke risk reduction....
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NCT04798261
STRIKE-PE: A Prospective, Multicenter Study of the Indigo Aspiration System Seeking to Evaluate the Long-Term Safety and Outcomes of Treating Pulmonary Embolism
This study is currently enrolling.Associated Conditions: Pulmonary EmbolismResearch Area: Heart, Lung and Vascular ResearchResearch Location: Orlando, FloridaYour study doctor has determined you have or have had a pulmonary embolism (PE). A PE is a blood clot in an artery or arteries in your lung. A clot can be life threatening if immediate action is not...
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NCT04807868
AVAIL: AdventHealth Research Institute Non-Alcoholic Fatty Liver Disease Biobank and Registry
This study is currently enrolling.Associated Conditions: Liver-NAFL, NASHResearch Area: Translational ResearchResearch Location: Orlando, FloridaNon-alcoholic fatty liver disease (NAFLD) is a common liver disease that leads to many health complications. Many people have this disease and do not know it. There are no medications available to...
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NCT04793958
A Randomized Phase 3 Study of MRTX849 in Combination with Cetuximab Versus Chemotherapy in Patients with Advanced Colorectal Cancer with KRAS G12C Mutation with Disease Progression On or After Standard First-Line Therapy
This study is currently enrolling.Associated Conditions: Colorectal CancerResearch Area: Clinical Cancer ResearchResearch Location: Orlando, FloridaThis is a study involving an investigational (experimental) drug called MRTX849, being developed by Mirati Therapeutics, Inc., which is the company that provides MRTX849 study drug and is funding and...
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NCT04754581
EXPET: Dynamic in vivo PET imaging and ex vivo biopsies from skeletal muscle and adipose tissue to investigate the effects of exercise on insulin resistance and mitochondrial energetics in type 2 diabetes
This study is currently enrolling.Associated Conditions: ExerciseResearch Area: Translational ResearchThe overall aim of this study is to investigate the effects of exercise training on skeletal muscle and adipose tissue insulin resistance in subjects with Type 2 Diabetes (T2D).
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NCT04221815
IMPROVE: MedStar Cardiovascular Research Network/IMPact on Revascularization Outcomes of intraVascular ultrasound guided treatment of complex lesions and Economic impact
This study is currently enrolling.Associated Conditions: AtherosclerosisResearch Area: Heart, Lung and Vascular ResearchResearch Location: Orlando, FloridaThe study will assess whether the use of IVUS improves subjects’ clinical outcomes at 1 year following this PCI procedure. These subjects will be compared to subjects who did not undergo such IVUS...