Nephritis

Kidney inflammation, or nephritis, can occur as the result of an autoimmune disease, infection or kidney disease, and interferes with the normal functioning of the kidneys. When this inflammation occurs due to the autoimmune disease known as lupus, the condition is called lupus nephritis, and a majority of patients diagnosed with lupus will experience kidney problems that require treatment at some point. If not treated promptly, nephritis can cause permanent kidney damage and lead to Stage 5 renal disease/renal failure, resulting in the need for dialysis and eventual kidney transplant. Common symptoms include discolored urine, quick weight gain and swelling in the hands, feet and eyelids. Nephritis is commonly treated with corticosteroid medication and immunosuppressant drugs.