Translational Research Clinical Trials
Search our team at AdventHealth Research Institute
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NCT07184086
The effect of cagrilintide and semaglutide combination treatment compared to a weight-loss inducing diet on energy metabolism in persons living with obesity: an open-label randomised study
This study is currently enrolling.Associated Conditions: Obesity & MetabolismResearch Area: Translational ResearchResearch Location: OrlandoStudy Purpose: The purpose of this study is to provide insight into the effect of Cagrisema on energy metabolism compared with low energy diet alone.
To be enrolled in this study, you must meet...
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NCT05773144
Adaptive Randomization of Aerobic Exercise During Chemotherapy in Colon Cancer
This study is currently enrolling.Associated Conditions: Exercise & BioenergeticsResearch Area: Translational ResearchResearch Location: OrlandoThe purpose of this research study is to determine if different durations of exercise can improve how well you tolerate chemotherapy for colon cancer.
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NCT05789433
Effects of Aerobic Exercise on Skeletal Muscle Remodeling in Colorectal Cancer
This study is currently enrolling.Associated Conditions: Exercise & BioenergeticsResearch Area: Translational ResearchResearch Location: OrlandoRESTORE-The purpose of this research study is to determine how different types of exercise change muscle tissue among people who have been diagnosed with colorectal cancer.
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SOMMA2: Study of Muscle, Mobility and Aging
This study is currently enrolling.Associated Conditions: Exercise & BioenergeticsResearch Area: Translational ResearchResearch Location: OrlandoThe goal of SOMMA is to better understand why some people lose muscle strength and mobility as they get older and how this might lead to difficulties with everyday activities. SOMMA is a national...
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NCT06745284
An active-comparator-controlled, open-label, parallel group study to evaluate the effect of survodutide on energy expenditure and fatty acid oxidation in subjects with obesity
This study is currently enrolling.Associated Conditions: Obesity & MetabolismResearch Area: Translational ResearchResearch Location: OrlandoA study to test whether survodutide improves how the body uses energy and breaks down fat in people with obesity.
To be enrolled in this study, you must meet certain requirements. You may be eligible...
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NCT06993454
ACELERATE-P: Acute exercise and endogenous glucose production in type 2 diabetes: Implications for glycemic control and treatment of hepatic steatosis
This study is currently enrolling.Associated Conditions: Exercise & BioenergeticsResearch Area: Translational ResearchResearch Location: OrlandoThe overall aim of this study is to investigate the effects of exercise on the amount of glucose that is made by your liver in people with and without Type 2 diabetes (T2D) and hepatic steatosis...
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NCT06602141
ATLAS: Assessments of Adipogenesis, Lipid Turnover and Cellular Composition in Adipose Tissue in Response to Endurance Exercise
This study is currently enrolling.Associated Conditions: Obesity & MetabolismResearch Area: Translational ResearchResearch Location: OrlandoStudy Purpose: The purpose of this research study is to study the effects of endurance exercise training on adipose (fat) tissue quality and insulin resistance in people with obesity.
To be enrolled...
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NCT05984238
RECET: A Multicenter, Double-blind, Sham-controlled Study for Assessing the Safety and Effectiveness of Endoscopic Intestinal Re-Cellularization Therapy in Individuals with Type 2 Diabetes
This study is currently enrolling.Associated Conditions: DiabetesResearch Area: Translational ResearchResearch Location: OrlandoStudy Purpose: To study changes in blood glucose control and weight loss in Type II Diabetics using Nutrition and Lifestyle Counseling combined with an investigational device called the ReCET...
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ENABLE: Clinical validation of islet autoantibody measurement in self-collected dried blood spot specimens
This study is currently enrolling.Associated Conditions: DiabetesResearch Area: Translational ResearchResearch Location: OrlandoStudy Purpose: Clinical validation of islet autoantibody measurement in self-collected dried blood spot specimens.
To be enrolled in this study, you must meet certain requirements. You may be...
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NCT06008977
EX-BOOST: Exercise to boost response to checkpoint blockade immunotherapy
This study is currently enrolling.Associated Conditions: Exercise & BioenergeticsResearch Area: Translational ResearchResearch Location: OrlandoStudy Purpose: To obtain a better understanding on how exercise can improve outcomes for patients with skin cancers.
To be enrolled in this study, you must meet certain requirements. You may be...
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COMET: ImpaCt Of shiftwork on METabolic Flexibility and Skeletal Muscle Clocks.
This study is currently enrolling.Associated Conditions: Exercise & BioenergeticsResearch Area: Translational ResearchResearch Location: OrlandoStudy Purpose: To determine how working a nighttime shift impacts your metabolism.
To be enrolled in this study, you must meet certain requirements. You may be eligible to participate if you meet the...
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NCT05197920
DREAM: Diabetes RElated to Acute pancreatitis and its Mechanisms (DREAM). An observational cohort study from the Type 1 Diabetes in Acute Pancreatitis Consortium (T1DAPC)
This study is currently enrolling.Associated Conditions: DiabetesResearch Area: Translational ResearchResearch Location: OrlandoStudy Purpose: The purpose of this research study is to find out how many people with acute pancreatitis develop diabetes. Risk factors for diabetes and the types of diabetes that occur after acute...