All Clinical Trials
Search our team at AdventHealth Research Institute
-
NCT07184086
The effect of cagrilintide and semaglutide combination treatment compared to a weight-loss inducing diet on energy metabolism in persons living with obesity: an open-label randomised study
This study is currently enrolling.Associated Conditions: Obesity & MetabolismResearch Area: Translational ResearchResearch Location: OrlandoStudy Purpose: The purpose of this study is to provide insight into the effect of Cagrisema on energy metabolism compared with low energy diet alone.
To be enrolled in this study, you must meet...
-
NCT05773144
Adaptive Randomization of Aerobic Exercise During Chemotherapy in Colon Cancer
This study is currently enrolling.Associated Conditions: Exercise & BioenergeticsResearch Area: Translational ResearchResearch Location: OrlandoThe purpose of this research study is to determine if different durations of exercise can improve how well you tolerate chemotherapy for colon cancer.
-
NCT05789433
Effects of Aerobic Exercise on Skeletal Muscle Remodeling in Colorectal Cancer
This study is currently enrolling.Associated Conditions: Exercise & BioenergeticsResearch Area: Translational ResearchResearch Location: OrlandoRESTORE-The purpose of this research study is to determine how different types of exercise change muscle tissue among people who have been diagnosed with colorectal cancer.
-
SOMMA2: Study of Muscle, Mobility and Aging
This study is currently enrolling.Associated Conditions: Exercise & BioenergeticsResearch Area: Translational ResearchResearch Location: OrlandoThe goal of SOMMA is to better understand why some people lose muscle strength and mobility as they get older and how this might lead to difficulties with everyday activities. SOMMA is a national...
-
NCT05666960
RISE: A single and repeat dosing study of the safety, drug exposure, and clinical activity of R-3750 in patients with mild to moderate ulcerative colitis
This study is currently enrolling.Associated Conditions: IBDResearch Area: Digestive Health and SurgeryResearch Location: OrlandoThe purpose of this study is to determine if R-3750 DP is safe and to determine how much R-3750 DP (what dosage) to give to people with UC.
-
NCT06527157
PROspective ACcrual To Investigate reprOductive cancers in womeN.
This study is currently enrolling.Associated Conditions: WomensResearch Area: Pediatric Research and Clinical TrialsResearch Location: OrlandoThe purpose of this clinical research study is to develop a non-invasive test to tell future women that they do not have endometrial cancer.
-
NCT06819007
A Phase 3, Open-label, Multicenter, Randomized Trial of Trastuzumab Deruxtecan with Bevacizumab Versus Bevacizumab Monotherapy as First-line Maintenance Therapy in HER2-Expressing Ovarian Cancer” GOG 3112/ DSI-T-DXd ENHERTU (DO-01); DESTINY-Ovarian01 (DO-01)] DS8201-772
This study is currently enrolling.Associated Conditions: GynecologyResearch Area: Clinical Cancer ResearchResearch Location: OrlandoThis study consists of two parts: Part 1 (safety run-in) and Part 2 (randomized part [like the flip of a coin]). The purpose of Part 1 is to learn more about the safety and tolerability of the...
-
NCT06745284
An active-comparator-controlled, open-label, parallel group study to evaluate the effect of survodutide on energy expenditure and fatty acid oxidation in subjects with obesity
This study is currently enrolling.Associated Conditions: Obesity & MetabolismResearch Area: Translational ResearchResearch Location: OrlandoA study to test whether survodutide improves how the body uses energy and breaks down fat in people with obesity.
To be enrolled in this study, you must meet certain requirements. You may be eligible...
-
NCT06745323
A Phase 2, Open-label, Randomized, Multicenter Study of Tarlatamab Dosing Regimens in Subjects with Small Cell Lung Cancer (SCLC) (DeLLphi-309)
This study is currently enrolling.Associated Conditions: ThoracicResearch Area: Clinical Cancer ResearchResearch Location: OrlandoThis study is being done to learn more about tarlatamab in people with Small Cell Lung Cancer (SCLC; a type of fast-growing cancer that forms in tissues of the lung and can spread to other parts of...
-
NCT05640999
A Phase II Study of Tailored Adjuvant Therapy in Pole-Mutated and p53-Wildtype/NSMP Early-Stage Endometrial Cancer (RAINBO BLUE & TAPER)
This study is currently enrolling.Associated Conditions: GynecologyResearch Area: Clinical Cancer ResearchResearch Location: Porter, ColoradoThis study is being done to answer the following question: Are there types of early-stage endometrial cancer that require less treatment than the usual approach? We are doing this study because we...
-
NCT05256225
A Phase II/III Study of Paclitaxel/Carboplatin Alone or Combined with Either Trastuzumab and Hyaluronidase-oysk (HERCEPTIN HYLECTA) or Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf (PHESGO) in HER2 Positive, Stage I-IV Endometrial Serous Carcinoma or Carcinosarcoma
This study is currently enrolling.Associated Conditions: GynecologyResearch Area: Clinical Cancer ResearchResearch Location: Porter, Colorado -
A Randomized, Open-label Phase 3 Study of Amivantamab + mFOLFOX6 or FOLFIRI Versus Cetuximab + mFOLFOX6 or FOLFIRI as First-line Treatment in Participants with RAS/RAF Wild-Type Unresectable or Metastatic Left-sided Colorectal Cancer (OrigAMI-2)
This study is currently enrolling.Associated Conditions: GastrointestinalResearch Area: Clinical Cancer ResearchResearch Location: AltamonteThe purpose of this study is to compare the effects of two anticancer drugs (amivantamab and cetuximab) when each is given in combination with standard colorectal cancer (CRC) chemotherapies. to...