About Primary CNS Lymphoma
When you or a family member is facing a lymphoma diagnosis, we'll be there to answer your questions, starting with the basics. Primary central nervous system (CNS) lymphoma is a disease in which malignant (cancerous) cells form in the lymph tissue of the brain and/or spinal cord.
Lymphoma is a disease in which cancer cells form in the lymph system. The lymph system is part of the immune system and is made up of the lymph, lymph vessels, lymph nodes, spleen, thymus, tonsils and bone marrow. Lymphocytes (carried in the lymph) travel in and out of the central nervous system. It is thought that some of these lymphocytes become malignant and cause lymphoma to form in the CNS.
Primary CNS lymphoma can start in the brain, spinal cord or meninges (the layers that form the brain's outer covering). Because the eye is so close to the brain, primary CNS lymphoma can also start in the eye (called ocular lymphoma). Learn more about the symptoms and risk factors below.
Symptoms and Risk Factors of Primary CNS Lymphoma
General symptoms can include:
- Changes in vision or a partial loss of vision
- Headache
- Loss of sensation in a particular area
- Muscle weakness in a particular area, for example, in one limb
- Nausea and vomiting
- Problems with balance
- Seizures
Primary CNS lymphoma is an uncommon form of lymphoma. The average age at diagnosis is around 60. It is slightly more common in people who have a weakened immune system, which might be caused by:
- HIV/AIDS
- Immunosuppressive treatments, including medications that suppress the immune system following an organ transplant or treatments for rheumatological conditions
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