Clinical Trials
Search our team at AdventHealth Research Institute
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Study of Muscle, Mobility and Aging (SOMMA2) Renewal
This study is not currently enrolling.Research Area: Translational ResearchResearch Location: Orlando, FloridaThe main purpose of SOMMA2 is to understand how the muscle changes as we age. We hope that this research project will help us understand why some people develop problems walking as they get older
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NCT04724018
DF/HCC 20-614 Combinatons of Sacituzumab govitecan plus enfortumab vedotin and pembrolizumab for metastatic urothelial carcinoma: the Double Antibody Drug conjugate (DAD) and Double Antibody Drug Conjugate with Immunotherapy (DAD-IO) Phase I/II trial
This study is not currently enrolling.Associated Conditions: Urothelial CancerResearch Area: Clinical Cancer ResearchResearch Location: Orlando, FloridaThis research is being done to study the safety and efficacy of two drug combinations. The first combination is Sacituzumab govitecan and enfortumab vedotin, and the second is Sacituzumab govitecan in...
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NCT06819007
A Phase 3, Open-label, Multicenter, Randomized Trial of Trastuzumab Deruxtecan with Bevacizumab Versus Bevacizumab Monotherapy as First-line Maintenance Therapy in HER2-Expressing Ovarian Cancer” GOG 3112/ DSI-T-DXd ENHERTU (DO-01); DESTINY-Ovarian01 (DO-01)] DS8201-772
This study is not currently enrolling.Associated Conditions: Ovarian, Fallopian, or Primary Peritoneum CancerResearch Area: Clinical Cancer ResearchResearch Location: Orlando, FloridaThis study consists of two parts: Part 1 (safety run-in) and Part 2 (randomized part [like the flip of a coin]). The purpose of Part 1 is to learn more about the safety and tolerability of the...
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NCT05929235
A Phase 1, First-in-Human, Dose-Escalation and Expansion Study of FX-909 in Patients With Advanced Solid Malignancies, Including Advanced Urothelial Carcinoma
This study is not currently enrolling.Associated Conditions: Multiple Tumor TypesResearch Area: Clinical Cancer ResearchResearch Location: Celebration, Florida -
NCT03142152
Assessment of the Carillon Mitral Contour System® in Treating Heart Failure with Functional Mitral Regurgitation
This study is not currently enrolling.Research Area: Heart, Lung and Vascular ResearchResearch Location: Tampa, FloridaThe purpose of this clinical study is to evaluate the safety and effectiveness of the Carillon Mitral Contour System in people who have mitral regurgitation resulting from heart failure.
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NCT06616974
A Phase 2, Double-blind, Randomized, Placebo-Controlled Study to Assess the Efficacy and Safety of TX000045 After 24 Weeks of Treatment in Patients With Pulmonary Hypertension Secondary to Heart Failure With Preserved Ejection Fraction (PH-HFpEF)
This study is not currently enrolling.Research Area: Heart, Lung and Vascular ResearchThe study Sponsor is developing the investigational (experimental) drug TX000045 as a potential new treatment for patients with high lung blood pressure due to heart failure.
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Discovery and Characterization of Genetic Risk Loci in Sjögren’s Syndrome
This study is not currently enrolling.Research Area: Pediatric Research and Clinical TrialsResearch Location: Orlando, Florida -
NCT06676072
Safety and effectiveness of the TactiFlex SE Catheter and Volt Pulsed Field Ablation (PFA) Generator in subjects with paroxysmal atrial fibrillation
This study is not currently enrolling.Research Area: Heart, Lung and Vascular ResearchResearch Location: Orlando, FloridaThe purpose of the study is to find out if the investigational TactiFlex PFA System, the device that is being studied, is safe and effective in treating adults like you who have atrial fibrillation
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NCT05463731
A Study of Remternetug Versus Placebo in Early Alzheimer’s Disease Participants at Risk for Cognitive and Functional Decline
This study is not currently enrolling.Research Area: Neuroscience ResearchResearch Location: Orlando, FloridaThis study is looking to assess the effect of remternetug versus
placebo on time to clinically meaningful
progression in participants with early AD. -
NCT06400342
The REVIVE-TAVR (Randomized Evaluation of Valve-In-Valve versus Explantation for failed Transcatheter Aortic Valve Replacement)
This study is not currently enrolling.Research Area: Heart, Lung and Vascular Research -
NCT06484114
REMAIN-1: A Prospective, Randomized, Double-Blind, Sham-Controlled, Multicenter, Pivotal Study to Assess the Efficacy of Revita Duodenal Mucosal Resurfacing (DMR) on Body Weight Maintenance in Participants with Obesity and Who Have Achieved at Least 15% Weight Loss on Tirzepatide Obesity Pharmacotherapy
This study is not currently enrolling.Research Area: Translational ResearchResearch Location: Orlando, FloridaREMAIN-1 The purpose of this research is to see if doing a procedure that temporarily removes the lining of your duodenum (first part of your small intestine) can help you keep from regaining weight...
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Retrospective Data Collection of Ultrasound Media from Subjects Implanted with Impella® Device
This study is not currently enrolling.Research Area: Heart, Lung and Vascular ResearchResearch Location: Tampa, Florida