Photo of Yury O. Nunez-Lopez, PhD

Yury O. Nunez-Lopez, PhD

Research Scientist

Research Area:

Expertise of Yury O. Nunez-Lopez, PhD

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Biography

​Over 25 years of valuable wet lab and bioinformatic experiences. Implemented and managed the entire research workflow, from developing research ideas and writing grant proposals to designing and performing experimental procedures, conducting high throughput data analyses, and publishing results in peer reviewed journals. Established the NGS section of a Cancer Pharmacogenomics laboratory from scratch: handled the research and negotiation process to purchase NGS instrument, conducted site preparation for installation, designed and implemented pipelines for data generation using commercial software and in-house developed R scripts. Contributed advanced understandings of biological principles underlying gene and microRNA regulation, cellular pathway analysis, comparative genomics, gene coexpression networks, and statistical modeling, among others. Currently studying metabolism, obesity, diabetes, cancer, and aging. Involved in translational research in the extracellular vesicle field. Expertise in microRNA profiling, transcriptomics, and proteomics.

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Education

Institute of Nuclear Sciences & Technology, Cuba

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Residency

Yale University School of Medicine, Research Associate

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Fellowship

Rutgers University, NJ

Publications of Yury O. Nunez-Lopez, PhD
  • The proteome and phosphoproteome of circulating extracellular vesicle-enriched preparations are associated with characteristic clinical features in type 1 diabetes
    , FRONTIERS IN ENDOCRINOLOGY

  • Extracellular vesicle proteomics and phosphoproteomics identify pathways for increased risk in patients hospitalized with COVID-19 and type 2 diabetes mellitus
    , DIABETES RESEARCH AND CLINICAL PRACTICE

  • Detectable Lipidomes and Metabolomes by Different Plasma Exosome Isolation Methods in Healthy Controls and Patients with Advanced Prostate and Lung Cancer
    , INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

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  • A comparative Proteomics Analysis Identified Differentially Expressed Proteins in Pancreatic Cancer-Associated Stellate Cell Small Extracellular Vesicles
    , MOLECULAR & CELLULAR PROTEOMICS

  • Coordinated regulation of gene expression and microRNA changes in adipose tissue and circulating extracellular vesicles in response to pioglitazone treatment in humans with type 2 diabetes
    , FRONTIERS IN ENDOCRINOLOGY

  • Proteomics and Phosphoproteomics of Circulating Extracellular Vesicles Provide New Insights into Diabetes Pathobiology
    , INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

  • Plasma miRNA Profile of Crohn's Disease and Rheumatoid Arthritis Patients
    , BIOLOGY-BASEL

  • Circulating microRNA profile in humans and mice with congenital GH deficiency
    , AGING CELL

  • Investigation of Extracellular Vesicles From SARS-CoV-2 Infected Specimens: A Safety Perspective
    , FRONTIERS IN IMMUNOLOGY

  • Profiling of tRNA Halves and YRNA Fragments in Serum and Tissue From Oral Squamous Cell Carcinoma Patients Identify Key Role of 5 ' tRNA-Val-CAC-2-1 Half
    , FRONTIERS IN ONCOLOGY