Search our team at AdventHealth Research Institute
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NCT05637801
A Randomized, Double-blind, Sham-controlled, Adaptive- Design Pivotal Study of Sensory Stimulation in Subjects with Alzheimer’s Disease
This study is currently enrolling.Associated Conditions: NeurodegenerativeResearch Area: Clinical Neuroscience ResearchResearch Location: Orlando, FloridaIn this study, researchers want to find out if sensory stimulation delivered using the Sensory Stimulation System may help slow disease progression in people with mild to moderate Alzheimer’s disease...
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NCT05463731
A Study of Remternetug Versus Placebo in Early Alzheimer’s Disease Participants at Risk for Cognitive and Functional Decline
This study is currently enrolling.Research Area: Clinical Neuroscience ResearchResearch Location: Orlando, FloridaThis study is looking to assess the effect of remternetug versus
placebo on time to clinically meaningful
progression in participants with early AD. -
NCT06170268
Alzheimer’s Association / “Alzheimer’s Network for Treatment and Diagnostics (ALZ-NET)”.
This study is currently enrolling.Associated Conditions: NeurodegenerativeResearch Area: Clinical Neuroscience Research -
K23 APATHY: Targeting Network Dysfunction in Apathy of Late-life Depression Using Digital Therapeutics
This study is currently enrolling.Research Area: Clinical Neuroscience ResearchResearch Location: Orlando, FloridaStudy Purpose: This study is exploring a new treatment to help improve depression in older adulthood. The study will look at the effects of a digital cognitive intervention on mood and brain health in...
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NCT04073563
Prospective, Randomized, Controlled, Blinded Pivotal Study In Subjects Undergoing A Transforaminal Lumbar Interbody Fusion (TLIF) At One Or Two Levels Using Infuse™ Bone Graft With an Intervertebral Body Fusion Device and Posterior Supplemental Fixation For The Treatment Of Symptomatic Degenerative Disease Of The Lumbosacral Spine
This study is currently enrolling.Research Area: Clinical Neuroscience ResearchResearch Location: Orlando, FloridaThe purpose of this study is to evaluate the Infuse™ Bone Graft in combination with other spinal devices and autograft bone (your own bone) to see if it is safe and effective when used in a TLIF...
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NCT06290141
A Phase 3, randomized, double-blind, study evaluating efficacy and safety of riliprubart versus intravenous immunoglobulin (IVIg) in participants with chronic inflammatory demyelinating polyneuropathy
This study is currently enrolling.Research Area: Clinical Neuroscience ResearchResearch Location: Orlando, FloridaA Phase 3, randomized, double-blind, study evaluating efficacy and safety of riliprubart versus intravenous immunoglobulin (IVIg) in participants with chronic inflammatory demyelinating polyneuropathy...
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NCT04408625
A Phase 1/2 Ascending Dose Study to Evaluate the Safety and Effects on Progranulin Levels of LY3884963 in Patients with Fronto-Temporal Dementia with Progranulin Mutations (FTD-GRN) (PROCLAIM)
This study is currently enrolling.Associated Conditions: AlzheimersResearch Area: Clinical Neuroscience ResearchResearch Location: Orlando, FloridaThe purpose of this open label study is to assess the safety, tolerability, and effects of LY3884963 on plasma (the liquid component of blood) and/or cerebrospinal fluid (CSF; fluid from the area...
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NCT04127578
Phase 1/2a Open-Label Ascending Dose Study to Evaluate the Safety and Effects of LY3884961 in Patients with Parkinson’s Disease with at Least One GBA1 Mutation (PROPEL)
This study is currently enrolling.Research Area: Clinical Neuroscience ResearchResearch Location: Orlando, FloridaParkinson’s disease is a slowly progressive and disabling disease of the central nervous system that causes problems with movement, such as shaking, stiffness, slow movement, and difficulty walking...
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NCT06132893
A Phase 2/3 Multicenter, Randomized, Double-Blind, Placebo-Controlled, Study to Evaluate the Efficacy, Safety and Tolerability of the BHV7000 in Subjects with Refractory Focal Onset Epilepsy
This study is currently enrolling.Research Area: Clinical Neuroscience ResearchResearch Location: Orlando, FloridaThis is a research study to test a new investigational drug. An investigational drug is one that is not approved by the United States Food and Drug Administration (FDA). The main purpose of this study...
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LAMBDA study: Longitudinal Assessment of Multidomain Brain data for early Detection of Alzheimer’s disease LAMBDA
This study is currently enrolling.Associated Conditions: AlzheimersResearch Area: Clinical Neuroscience ResearchResearch Location: Orlando, FloridaStudy Purpose: This study will be examining changes in memory and mental function and several biological variables in aging. Examining the biology underlying memory changes could influence our...
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NCT03671889
Assessment of Safety and Efficacy of Exablate Blood-Brain Barrier Disruption for the Treatment of Patients with Probable Alzheimer’s Disease
This study is currently enrolling.Research Area: Clinical Neuroscience ResearchResearch Location: Celebration, FloridaThe result of this study will help us determine whether blood-brain barrier disruption (BBBD) with Exablate is a safe procedure in the brains of patients with Alzheimer’s Disease. The purpose of this...
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NCT05301140
Vivistim Registry for Paired VNS Therapy (GRASP)
This study is currently enrolling.Research Area: Clinical Neuroscience ResearchResearch Location: Orlando, FloridaThe purpose of this particular registry is to collect information about patients who have had a stroke and still have upper-limb difficulties. This registry includes information before and after...