Neuroscience Research Clinical Trials
Search our team at AdventHealth Research Institute
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NCT06744920
A randomized, double-blind, placebo-controlled phase III study to evaluate the efficacy, safety, and tolerability of remibrutinib in patients with generalized Myasthenia Gravis, followed by an open-label extension phase
This study is currently enrolling.Associated Conditions: Brain Health - NeuromuscularResearch Area: Neuroscience ResearchResearch Location: OrlandoThe purpose of this study is to evaluate the efficacy, safety and tolerability of remibrutinib in patients with generalized Myasthenia Gravis (gMG) who are acetylcholine receptor positive (AChR+)...
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NCT06170268
Alzheimer’s Association / “Alzheimer’s Network for Treatment and Diagnostics (ALZ-NET)”.
This study is currently enrolling.Associated Conditions: Brain Health - MemoryResearch Area: Neuroscience ResearchResearch Location: Orlando -
K23 APATHY: Targeting Network Dysfunction in Apathy of Late-life Depression Using Digital Therapeutics
This study is currently enrolling.Associated Conditions: Translational NeuroscienceResearch Area: Neuroscience ResearchResearch Location: OrlandoStudy Purpose: This study is exploring a new treatment to help improve depression in older adulthood. The study will look at the effects of a digital cognitive intervention on mood and brain health in...
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NCT04073563
Prospective, Randomized, Controlled, Blinded Pivotal Study In Subjects Undergoing A Transforaminal Lumbar Interbody Fusion (TLIF) At One Or Two Levels Using Infuse™ Bone Graft With an Intervertebral Body Fusion Device and Posterior Supplemental Fixation For The Treatment Of Symptomatic Degenerative Disease Of The Lumbosacral Spine
This study is currently enrolling.Associated Conditions: Spine HealthResearch Area: Neuroscience ResearchResearch Location: OrlandoThe purpose of this study is to evaluate the Infuse™ Bone Graft in combination with other spinal devices and autograft bone (your own bone) to see if it is safe and effective when used in a TLIF...
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NCT06290141
A Phase 3, randomized, double-blind, study evaluating efficacy and safety of riliprubart versus intravenous immunoglobulin (IVIg) in participants with chronic inflammatory demyelinating polyneuropathy
This study is currently enrolling.Associated Conditions: Brain Health - NeuromuscularResearch Area: Neuroscience ResearchResearch Location: OrlandoA Phase 3, randomized, double-blind, study evaluating efficacy and safety of riliprubart versus intravenous immunoglobulin (IVIg) in participants with chronic inflammatory demyelinating polyneuropathy...
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NCT04408625
A Phase 1/2 Ascending Dose Study to Evaluate the Safety and Effects on Progranulin Levels of LY3884963 in Patients with Fronto-Temporal Dementia with Progranulin Mutations (FTD-GRN) (PROCLAIM)
This study is currently enrolling.Associated Conditions: Brain Health - MemoryResearch Area: Neuroscience ResearchResearch Location: OrlandoThe purpose of this open label study is to assess the safety, tolerability, and effects of LY3884963 on plasma (the liquid component of blood) and/or cerebrospinal fluid (CSF; fluid from the area...
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NCT04127578
Phase 1/2a Open-Label Ascending Dose Study to Evaluate the Safety and Effects of LY3884961 in Patients with Parkinson’s Disease with at Least One GBA1 Mutation (PROPEL)
This study is currently enrolling.Associated Conditions: Brain Health - Movement DisordersResearch Area: Neuroscience ResearchResearch Location: OrlandoParkinson’s disease is a slowly progressive and disabling disease of the central nervous system that causes problems with movement, such as shaking, stiffness, slow movement, and difficulty walking...
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NCT06189963
NKGen Biotech, Inc. “A Phase 1/2a Study to Evaluate the Safety, Tolerability and Exploratory Efficacy of SNK01 in Participants with Moderate Alzheimer’s Disease (Study SNK01-AD01)”
This study is currently enrolling.Associated Conditions: Brain Health - MemoryResearch Area: Neuroscience ResearchResearch Location: OrlandoThe primary purpose of this research is to evaluate the safety of NK cell therapy when given alone. A secondary objective is to evaluate any preliminary efficacy by the change in cognitive assessment...
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LAMBDA study: Longitudinal Assessment of Multidomain Brain data for early Detection of Alzheimer’s disease LAMBDA
This study is currently enrolling.Associated Conditions: Translational NeuroscienceResearch Area: Neuroscience ResearchResearch Location: OrlandoStudy Purpose: This study will be examining changes in memory and mental function and several biological variables in aging. Examining the biology underlying memory changes could influence our...
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NCT03671889
Assessment of Safety and Efficacy of Exablate Blood-Brain Barrier Disruption for the Treatment of Patients with Probable Alzheimer’s Disease
This study is currently enrolling.Associated Conditions: Brain Health - MemoryResearch Area: Neuroscience ResearchResearch Location: CelebrationThe result of this study will help us determine whether blood-brain barrier disruption (BBBD) with Exablate is a safe procedure in the brains of patients with Alzheimer’s Disease. The purpose of this...
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NCT05301140
Vivistim Registry for Paired VNS Therapy (GRASP)
This study is currently enrolling.Associated Conditions: NeurosurgeryResearch Area: Neuroscience ResearchResearch Location: OrlandoThe purpose of this particular registry is to collect information about patients who have had a stroke and still have upper-limb difficulties. This registry includes information before and after...
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MSBASE: An international registry dedicated to evaluating outcomes data in multiple sclerosis (MS) and other neuroimmunological diseases (NIDs)
This study is currently enrolling.Associated Conditions: Brain Health - Multiple SclerosisResearch Area: Neuroscience ResearchResearch Location: OrlandoThe MSBase Registry is a research registry. Research registries are also known as a research databases. They collect information about lots of people, often who all have the same health condition. The...