Heart, Lung and Vascular Research Clinical Trials
Search our team at AdventHealth Research Institute
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NCT06481891
A Randomized, Double-blind, Placebo-controlled, Parallel-group, Multicenter Study to Evaluate the Efficacy and Safety of SOtaglifloziN in symptomATic obstructive And non-obstructive Hypertrophic CardioMyopathy (SONATA-HCM)
This study is currently enrolling.Associated Conditions: Heart FailureResearch Area: Heart, Lung and Vascular ResearchResearch Location: OrlandoHypertrophic cardiomyopathy (HCM) is a common heart condition that can trigger sudden death, irregular heartbeats, and heart failure. The condition is linked to genes and causes the heart muscle to...
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NCT05932615
Evaluation of the Navitor Transcatheter Heart Valve in Low and Intermediate Risk Patients who have Severe, Symptomatic, Aortic Stenosis Requiring Aortic Valve Replacement
This study is currently enrolling.Associated Conditions: Structural HeartResearch Area: Heart, Lung and Vascular ResearchResearch Location: OrlandoAortic stenosis is a type of heart valve disease where the valve located between the lower left heart chamber and the body’s main artery (aorta) becomes narrowed and cannot open completely. This...
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NCT06055920
PEERLESS II Study RCT of FlowTriever vs. Anticoagulation Alone in Pulmonary Embolism
This study is currently enrolling.Associated Conditions: Pulmonary EmbolismResearch Area: Heart, Lung and Vascular ResearchResearch Location: OrlandoYou are being asked to take part in this study because you have a pulmonary embolism (PE). A PE is a blood clot trapped in your lung. You are being asked to participate in the PEERLESS II Study...
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NCT06041594
Treating Pulmonary Embolism with Laguna Thrombectomy System (TRUST)
This study is currently enrolling.Associated Conditions: Pulmonary EmbolismResearch Area: Heart, Lung and Vascular ResearchResearch Location: TampaThe purpose of this research study is to show whether an investigational device, called the Laguna™ Thrombectomy System, is safe and effective for the treatment of pulmonary embolism. The Laguna™...
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NCT05677100
DiuRetics Alone vs. AortIx ENdovascular Device for Acute Heart Failure (DRAIN HF)
This study is currently enrolling.Associated Conditions: Heart FailureResearch Area: Heart, Lung and Vascular ResearchResearch Location: TampaENROLLING IN TAMPA
The purpose of this research is to evaluate the investigational Aortix System. The Aortix System is not approved by the FDA. The system has been designed for use in patients...
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NCT05685303
ALLAY-HF: Safety and Efficacy of the Alleviant System for No-Implant Interatrial Shunt Creation in Patients with Chronic Heart Failure
This study is currently enrolling.Associated Conditions: Heart FailureResearch Area: Heart, Lung and Vascular ResearchResearch Location: OrlandoTo evaluate the safety and efficacy of the Alleviant ALV1 System in
patients with chronic heart failure (HF) and preserved ejection fraction
(HFpEF) or mildly reduced ejection fraction (HFmrEF), who... -
NCT05064709
Assessment of Implantable CCM in the Heart Failure Group with Higher Ejection Fraction
This study is currently enrolling.Associated Conditions: ElectrophysiologyResearch Area: Heart, Lung and Vascular ResearchResearch Location: OrlandoYour doctor has diagnosed you with HF. You are being asked to consider voluntary participation in a research study of CCM treatment with the Optimizer System, sponsored by Impulse Dynamics (USA) Inc...
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NCT04796337
SOTERIA - An Open-Label Long-Term Follow-Up Study to Evaluate the Effects of Sotatercept when Added to Background Pulmonary Arterial Hypertension (PAH) Therapy for the Treatment of PAH
This study is currently enrolling.Associated Conditions: Pulmonary HypertensionResearch Area: Heart, Lung and Vascular ResearchResearch Location: OrlandoWe are asking you to take part in this study because you are currently in a study with sotatercept and we want to find out if continuing to take sotatercept is safe and effective over a long period of...
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NCT04226547
CATALYST - Clinical trial of atrial fibrillation patients comparing left atrial appendage occlusion therapy to non-vitamin K antagonist oral anticoagulants
This study is currently enrolling.Associated Conditions: ElectrophysiologyResearch Area: Heart, Lung and Vascular ResearchResearch Location: OrlandoThe purpose of this research study is to compare the safety and effectiveness of the Amulet device compared to non-vitamin K antagonist oral anticoagulants (NOACs) for ischemic stroke risk reduction....
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NCT04798261
STRIKE-PE: A Prospective, Multicenter Study of the Indigo Aspiration System Seeking to Evaluate the Long-Term Safety and Outcomes of Treating Pulmonary Embolism
This study is currently enrolling.Associated Conditions: Pulmonary EmbolismResearch Area: Heart, Lung and Vascular ResearchResearch Location: OrlandoYour study doctor has determined you have or have had a pulmonary embolism (PE). A PE is a blood clot in an artery or arteries in your lung. A clot can be life threatening if immediate action is not...
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NCT04071327
PHAR - Pulmonary Hypertension Association Registry
This study is currently enrolling.Associated Conditions: Pulmonary HypertensionResearch Area: Heart, Lung and Vascular ResearchResearch Location: OrlandoWe are asking you to be included in the Pulmonary Hypertension Association (PHA) Registry (PHAR). This is a national project about people who have pulmonary hypertension (PH). We are asking you to...