Clinical Trials
Search our team at AdventHealth Research Institute
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SOMMA2: Study of Muscle, Mobility and Aging
This study is currently enrolling.Research Area: Translational ResearchResearch Location: Orlando, FloridaThe goal of SOMMA is to better understand why some people lose muscle strength and mobility as they get older and how this might lead to difficulties with everyday activities. SOMMA is a national...
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NCT06527157
PROspective ACcrual To Investigate reprOductive cancers in womeN.
This study is currently enrolling.Research Area: Clinical Cancer ResearchResearch Location: Orlando, FloridaThe purpose of this clinical research study is to develop a non-invasive test to tell future women that they do not have endometrial cancer.
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NCT06745284
An active-comparator-controlled, open-label, parallel group study to evaluate the effect of survodutide on energy expenditure and fatty acid oxidation in subjects with obesity
This study is currently enrolling.Research Area: Translational ResearchResearch Location: Orlando, FloridaA study to test whether survodutide improves how the body uses energy and breaks down fat in people with obesity.
To be enrolled in this study, you must meet certain requirements. You may be eligible...
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A Randomized, Open-label Phase 3 Study of Amivantamab + mFOLFOX6 or FOLFIRI Versus Cetuximab + mFOLFOX6 or FOLFIRI as First-line Treatment in Participants with RAS/RAF Wild-Type Unresectable or Metastatic Left-sided Colorectal Cancer (OrigAMI-2)
This study is currently enrolling.Associated Conditions: Colorectal CancerResearch Area: Clinical Cancer ResearchResearch Location: Altamonte, FloridaThe purpose of this study is to compare the effects of two anticancer drugs (amivantamab and cetuximab) when each is given in combination with standard colorectal cancer (CRC) chemotherapies. to...
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NCT05675410
A Randomized Phase 3 Interim Response Adapted Trial Comparing Standard Therapy with Immuno-oncology Therapy for Children and Adults with Newly Diagnosed Stage I and II Classic Hodgkin Lymphoma
This study is currently enrolling.Associated Conditions: Pediatric CancerResearch Area: Pediatric Research and Clinical TrialsResearch Location: Orlando, Florida -
NCT06014762
Open-Label, Multicenter, Phase 1 Study to Assess the Safety of P-CD19CD20-ALLO1 in Subjects with Selected Relapsed/Refractory B cell Malignancies
This study is currently enrolling.Research Area: Clinical Cancer ResearchResearch Location: Orlando, FloridaThe purpose of this study is to find out if an investigational treatment called, P-CD19CD20-ALLO1, is safe and will help treat people with one of the following B cell malignancies: diffuse large B...
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NCT04066348
Clinical Trial of Etanercept (TNF-a Blocker) for Treatment of Blast-Induced Tinnitus
This study is currently enrolling.Research Area: Digestive Health and SurgeryResearch Location: Celebration, FloridaThe purpose of this multi-site research study is to determine if Etanercept, compared to a placebo, significantly reduces the severity of tinnitus (ringing in the ears) associated with history of...
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NCT06707688
Pre-market IDE study of the Amulet™ 2 LAA Occluder VERITAS Study
This study is currently enrolling.Associated Conditions: ElectrophysiologyResearch Area: Heart, Lung and Vascular ResearchThe purpose of this research study is to see how well the experimental Amulet 2 device works and how well tolerated it is. The Amulet 2 device is used in patients with an irregular heartbeat that is...
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NCT05637801
A Randomized, Double-blind, Sham-controlled, Adaptive- Design Pivotal Study of Sensory Stimulation in Subjects with Alzheimer’s Disease
This study is currently enrolling.Associated Conditions: NeurodegenerativeResearch Area: Neuroscience ResearchResearch Location: Orlando, FloridaIn this study, researchers want to find out if sensory stimulation delivered using the Sensory Stimulation System may help slow disease progression in people with mild to moderate Alzheimer’s disease...
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NCT05514717
A Phase 1, First-in-Human, Dose Escalation and Expansion, Multicenter Study of XMT-2056 in Participants with Advanced/Recurrent Solid Tumors that Express HER2
This study is currently enrolling.Associated Conditions: Metastatic Solid TumorsResearch Area: Clinical Cancer Research -
NCT06667076
A Phase 2, Open-Label, Multi-cohort Study of Subcutaneous Amivantamab in Combination with Lazertinib as First-Line Treatment, or Subcutaneous Amivantamab in Combination with Platinum-based Chemo as Second-line Treatment, in Participants with EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer
This study is currently enrolling.Associated Conditions: Lung CancerResearch Area: Clinical Cancer ResearchThe purpose of this study is to help researchers understand more about the possible effectiveness and safety of the combination of amivantamab and lazertinib in patients with non-small cell lung...
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NCT06172478
A Phase 2, Multicenter, Multicohort, Open-Label, Proof of Concept Study of Patritumab Deruxtecan (HER3-DXd; U3-1402) in Subjects With Locally Advanced or Metastatic Solid Tumors
This study is currently enrolling.Associated Conditions: Multiple Tumor TypesResearch Area: Clinical Cancer ResearchThe purpose of this study is to learn more about an investigational drug called patritumab deruxtecan (also known as HER3-DXd or U3-1402), also referred to as “study drug” or “study treatment”...