AdventHealth Tampa Leads National Research on Female Heart Disease

A female doctor is seated, listening to a senior woman's heart with a stethoscope.

Tampa, FL – Heart disease is the number one killer of men and women, claiming over 600,000 lives each year in the U.S. In women particularly, there is still a lot unknown. AdventHealth Pepin Heart Institute, part of AdventHealth Tampa, is championing a new trial called the WARRIOR Trial. It is the nation’s first large, randomized controlled research study for the ongoing issue of women who have chest pain or other symptoms of heart disease but no significant blockage on testing. Research has found that many such women are often released from cardiology care untreated, but those same women have very high rates of stroke, heart failure and death.

The WARRIOR Trial will look at women 40 and older who have shown signs of coronary heart disease and exhibit symptoms such as chest pains and shortness of breath, but do not have artery blockage present in tests.

“The WARRIOR Trial could be a game changer for how we diagnose and treat women with certain types of heart disease,” said Dr. Charles Lambert, Medical Director of AdventHealth Pepin Heart Institute and Dr. Kiran C. Patel Research Institute. “What we learn here could ultimately provide guidelines for treatment of women without obstructive coronary disease and save many lives.”

The WARRIOR Trial will study both lifestyle changes, and intensive treatment with medications such as statins, ACE inhibitors, PCSK9 inhibitors, and aspirin.

“AdventHealth Tampa is committed to pioneering leading-edge research and we are currently the first and only site of national trials for heart disease,” said Brian Adams, President and CEO, AdventHealth Tampa. “We are dedicated to finding ways for people in our communities, and across the country, lead longer, healthier lives.”

AdventHealth Pepin Heart Institute is currently accepting women to join the trial. Interested participants can call Call813-610-8110 to find out if they qualify. For full details on the trial, please click here.

About AdventHealth West Florida Division
The West Florida Division of AdventHealth is a 1,810 bed health care system currently comprised of ten acute-care hospitals including AdventHealth Carrollwood, AdventHealth Dade City, AdventHealth Lake Placid, AdventHealth North Pinellas, AdventHealth Ocala, AdventHealth Sebring, AdventHealth Tampa, AdventHealth Wauchula, AdventHealth Wesley Chapel and AdventHealth Zephyrhills, as well as three freestanding offsite Emergency Rooms including AdventHealth Central Pasco ER, AdventHealth Palm Harbor ER and AdventHealth TimberRidge ER. Additionally, it has one post-acute care facility, AdventHealth at Connerton Long Term Acute Care, over 45 multi-specialty AdventHealth Physician Group practices, 15 AdventHealth Express Care at Walgreens clinics and 6 AdventHealth Centra Care Urgent Care Centers. The West Florida Division also provides home health care in Hillsborough, Pasco, Pinellas, Hernando, and Polk Counties, as well as parts of Sumter County. For more information, go to

About AdventHealth Tampa

AdventHealth Tampa is a not-for-profit 536-bed tertiary hospital specializing in Digestive Health, Cardiovascular Medicine, Neuroscience, Orthopedics, Women’s Services, Pediatrics, Oncology, Endocrinology, Bariatrics, Wound Healing, Sleep Medicine and General Surgery, including minimally invasive and robotic-assisted procedures. Also located at AdventHealth Tampa is the renowned AdventHealth Pepin Heart Institute, a recognized leader in cardiovascular disease prevention, diagnosis, treatment and leading-edge research. The addition of the Doc1st ER shows that Florida Hospital Tampa is committed to providing compassionate and quality healthcare. For more information, visit

About AdventHealth Pepin Heart Institute and Dr. Kiran C. Patel Research Institute

AdventHealth Pepin Heart Institute, located at AdventHealth Tampa, is a free-standing cardiovascular institute providing comprehensive care for patients with heart, valve, and vascular issues. Leading the way with the first accredited chest pain emergency room in Tampa Bay, the institute was among an elite few in the state of Florida chosen to perform the first Transcatheter Aortic Valve Replacement (TAVR) procedures and was the first in Tampa to offer the Watchman procedure to prevent blood clots in patients with atrial fibrillation. AdventHealth Pepin Heart Institute and the Dr. Kiran C. Patel Research Institute are exploring and conducting leading-edge research to develop breakthrough treatments long before they are available in most other hospitals. To learn more, visit