A Guide to Safely Using Common Medications During Pregnancy

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When you’re expecting, your and your baby’s health is your top priority — and it’s ours, too. We know that even something as simple as taking cold medicine like Robitussin during pregnancy can feel like a big decision. Many over-the-counter (OTC) medications that are normally safe are not recommended during pregnancy.

Lauren Kauvar, MD, a Littleton obstetrician with AdventHealth Medical Group OB/GYN at Littleton, is here to provide expert guidance on which medications are considered safe during pregnancy and which should be avoided.

This guide answers common questions about medication safety during pregnancy, including whether it’s safe to take Robitussin during pregnancy and other frequently used OTC medications.

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Is it safe to take Robitussin during pregnancy?

Robitussin, a popular cough suppressant, is often used to relieve congestion and coughing. Many women experience persistent coughs during pregnancy due to increased nasal congestion and postnasal drip, making safe cough relief an important consideration.

“Plain Robitussin, which contains dextromethorphan, is generally considered safe during pregnancy,” Dr. Kauvar says.

However, some formulas contain additional active ingredients like pseudoephedrine or guaifenesin, which may not be safe. Always check the label and choose a formulation that contains only dextromethorphan. If you’re unsure, it’s important that you consult your doctor to keep yourself and your little one safe before taking any cough medication.

Is hyaluronic acid safe to take during pregnancy?

Hyaluronic acid is a popular ingredient in skin care products known for its hydrating properties. Fortunately, Dr. Kauvar says, “Topical hyaluronic acid is safe to use during pregnancy.” It doesn’t penetrate the skin or enter the bloodstream, so it poses little risk.

However, she advises against injectable forms of hyaluronic acid, including dermal fillers, during pregnancy. These treatments have not been widely studied in pregnant women, and the body’s response to fillers can change due to hormonal fluctuations.

Is Zofran safe during pregnancy?

Zofran, a popular brand of ondansetron, is sometimes prescribed to treat severe nausea and vomiting for pregnant women. Dr. Kauvar says, “Zofran is commonly used when first-line treatments like vitamin B6 and doxylamine aren’t effective.”

While Zofran is generally considered safe, some studies have questioned its use in early pregnancy. Certain research suggests a possible link between early Zofran use and a slightly increased risk of birth defects, although findings are uncertain. If prescribed, your doctor will determine the appropriate dosage based on your needs. It’s important that you follow the proper dosage to keep you and your family safe.

Is Azo safe to take while pregnant?

Azo is an OTC medication used to relieve urinary tract discomfort. However, it shouldn’t be used during pregnancy. “Azo contains phenazopyridine, which is not recommended during pregnancy due to potential risks to the baby,” Dr. Kauvar says.

Instead, she recommends seeking medical treatment for UTIs rather than relying on symptom relief alone. Untreated UTIs can lead to kidney infections or other complications, making it essential to consult a doctor for safe antibiotic treatment.

Is amoxicillin safe during pregnancy?

Amoxicillin is a common antibiotic used for treating bacterial infections. “Amoxicillin is considered safe to use during pregnancy. It’s often prescribed for UTIs, sinus infections and other bacterial illnesses,” Dr. Kauvar assures us.

As with any medication, it’s important that you take antibiotics only when prescribed by your doctor. Completing the full course of antibiotics as directed is crucial to ensure the infection is fully treated and to prevent antibiotic resistance.

Is melatonin safe during pregnancy?

Melatonin is a natural sleep aid, but its safety during pregnancy remains unclear. “There isn’t enough research to confirm whether melatonin is completely safe during pregnancy,” Dr. Kauvar says. For trouble sleeping, she suggests improving your sleep hygiene, using relaxation techniques and discussing other safe options with your doctor. Cognitive behavioral therapy for insomnia and prenatal yoga are other drug-free options you can explore.

Is ibuprofen safe to take during pregnancy?

Dr. Kauvar tells us that ibuprofen is not safe to take during pregnancy. “Ibuprofen can reduce amniotic fluid levels and lead to kidney problems in the baby,” she says. Dr. Kauvar strongly advises against using Advil, Motrin and other non-steroidal anti-inflammatory drugs (NSAIDs) during pregnancy, especially in the third trimester.

For pain relief, acetaminophen, such as Tylenol, is the better option. If ibuprofen was taken before knowing about the pregnancy, talk to your doctor to assess any potential risks.

Is Benadryl safe to take during pregnancy?

Colorado’s dry climate and seasonal pollen can make allergies a frequent concern for pregnant women. Benadryl is a common diphenhydramine brand that is commonly used for allergies and as a sleep aid. However, you should steer clear of diphenhydramine during pregnancy — especially if you want to avoid drowsiness.

“If you need allergy relief, discuss other antihistamine options with your doctor. Non-drowsy alternatives like loratadine, the active ingredient in Claritin, may be recommended for daily allergy management,” says Dr. Kauvar.

Is Flonase safe during pregnancy?

With Colorado’s high pollen counts and occasional wildfire smoke, many women rely on year-round allergy medications like Flonase. Flonase is a common brand of fluticasone, a steroid nasal spray used to treat allergies. “Flonase is considered safe for pregnancy when used as directed,” Dr. Kauvar says. That’s because it works locally in the nasal passages and has minimal absorption into the bloodstream.

If allergy symptoms persist despite Flonase use, talk to your doctor about other safe treatment options.

Is Tylenol safe to take during pregnancy?

Tylenol is a common brand of acetaminophen used to relieve pain. Dr. Kauvar tells us, “Tylenol is the safest option for pain relief in pregnancy when used in appropriate dosages.”

However, prolonged or excessive use should be discussed with your doctor. Recent studies have raised concerns about the potential long-term developmental effects of frequent use, so moderation is key.

Is medical marijuana safe during pregnancy?

Although both medicinal and recreational marijuana use is legal in Colorado, it’s not recommended during pregnancy. “Marijuana crosses the placenta, and research suggests it may impact fetal brain development,” Dr. Kauvar says.

THC, the active ingredient in marijuana, can affect the baby’s nervous system and has been linked to lower birth weight and developmental delays. If you use marijuana for medical reasons, consult your doctor for safer alternatives to use during pregnancy.

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Natural Remedies and Alternatives to Medication

Many pregnant women prefer to minimize medication use whenever possible. Fortunately, there are several natural approaches to managing common pregnancy symptoms. These remedies can offer relief while reducing potential risks associated with medications. Some natural remedies include:

  • Applying heat packs, practicing prenatal yoga or getting a prenatal massage for pain relief
  • Trying ginger, acupressure wristbands or vitamin B6 for nausea relief
  • Using saline nasal sprays, a humidifier and warm teas with honey for cold symptom relief

It’s important that you talk to your doctor before pursuing any natural remedy to make sure it’s safe for you and your baby.

Your Ever-Present Health Companion Throughout Your Pregnancy

When it comes to taking medications during pregnancy, safety is key. If you have concerns about other medications, always check with your primary care provider first.

For personalized pregnancy care, schedule an appointment with AdventHealth Medical Group OB/GYN at Littleton by calling our front desk at Call720-922-6240 today. Our experienced team is here to support you every step of the way. You and your baby are in good hands.

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