REST: The role of type 2 diabetes on skeletal muscle atrophy and recovery following bed rest in older adults

Study Purpose: To better understand the role of Type 2 Diabetes on skeletal muscle atrophy and recovery following bed rest. Study Duration: 14 weeks Study Commitment: 2 Screening Visits 5 Pre-Bedrest Visits 10 Consecutive Days of Bedrest 8 Weeks of Outpatient Exercise Recovery Age: 60-80 years old Sex: Male and Female Conditions/Eligibility: We are seeking healthy participants and type 2 diabetics. Study Procedures: Physical exam, vital signs, height/weight/BMI Electrocardiogram (ECG) Lab specimen collection (blood and urine) DEXA and MRI Exercise testing (Questionnaires, Hand grip Strength, VO2 Max) Tissue sampling (muscle) Compensation: $10,000