Translational Research Clinical Trials

Study Purpose: The purpose of this study is to look at gene expression changes to insulin stimulation in different cells and areas of skeletal muscle and how they are affected by obesity and insulin...

MCD-1 Study Purpose-The purpose of this study is to look at how insulin (a hormone that helps the cells get energy from sugar) affects blood flow in the leg and in the heart and how an investigational...

Study Purpose: We are doing PRECIDENTD to learn more about diabetes medications that also reduce the risk of heart and kidney disease in people with type 2 diabetes.
Study Duration: 8 years
Study...

Study Purpose: The purpose of this study is to find out if a drug called sotagliflozin (SOTA) can slow kidney function decline in persons with type 1 diabetes and moderate to severe diabetic kidney...

iTREAT Study Purpose: The purpose of this study is to compare the safety and effectiveness of two different ways to treat asthma. The first way is adding inhaled corticosteroids to your rescue...

The goal of SOMMA is to better understand why some people lose muscle strength and mobility as they get older and how this might lead to difficulties with everyday activities. SOMMA is a national...

CLEAR Study Purpose: Hypoglycemia unawareness is a condition where someone with type 1 diabetes can’t feel their low blood glucose levels, which means someone else might need to provide assistance to...

Study Purpose: To investigate the effects of exercise on the amount of glucose that is made by your liver in people with Type 2 diabetes (T2D) and fatty liver and those without. Study Duration: 4...

Study Purpose: The purpose of this research study is to study the effects of endurance exercise training on adipose (fat) tissue quality and insulin resistance in people with obesity.

To be enrolled...

Study Purpose: The purpose of this research study is to find out how many people with acute pancreatitis develop diabetes. Risk factors for diabetes and the types of diabetes that occur after acute...

You are being asked to be in a research study called the TrialNet Natural History Study of the Development of Type 1 Diabetes. As you know, TrialNet is an international research group dedicated to the...