Clinical Trials
Search our team at AdventHealth Research Institute
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NCT06101745
A Phase 2/3 randomized controlled semi-blinded trial to investigate safety and effectiveness in visualization of the ureters with nizaracianine triflutate, administered intravenously in up to three divided doses, in participants (18 years or older) undergoing abdominopelvic surgical procedures [TRIPHASE Trial]
This study is currently enrolling.Associated Conditions: Surgical HealthResearch Area: Digestive Health and SurgeryResearch Location: OrlandoThe purpose of this research is to study the safety and effectiveness of an experimental research drug called Nizaracianine triflutate (nizaracianine) (study drug) when it is used to visualize the... -
AdventHealth Research Institute Lipedema Biobank and Registry
This study is currently enrolling.Associated Conditions: PlasticsResearch Area: Digestive Health and SurgeryResearch Location: Orlando -
Determining cell- and spatially-distinct skeletal muscle transcriptional aberrations in insulin resistance
This study is currently enrolling.Associated Conditions: Exercise & BioenergeticsResearch Area: Translational ResearchResearch Location: OrlandoStudy Purpose: The purpose of this study is to look at gene expression changes to insulin stimulation in different cells and areas of skeletal muscle and how they are affected by obesity and insulin...
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NCT06459869
A multicentre, open label, non-randomized, phase 1b trial of NG-350A, a tumourselective anti-CD40-expressing adenoviral vector, in combination with chemoradiotherapy in locally advanced rectal cancer (FORTRESS)
This study is currently enrolling.Associated Conditions: GastrointestinalResearch Area: Clinical Cancer ResearchResearch Location: OrlandoThe purpose of this research is to test an investigational drug called NG-350A as a possible treatment for locally advanced rectal cancer (LARC). An investigational drug is one that has not been... -
NCT05478707
THERAPEUTIC STRATEGIES FOR MICROVASCULAR DYSFUNCTION IN TYPE 1 DIABETES
This study is currently enrolling.Associated Conditions: DiabetesResearch Area: Translational ResearchResearch Location: OrlandoMCD-1 Study Purpose-The purpose of this study is to look at how insulin (a hormone that helps the cells get energy from sugar) affects blood flow in the leg and in the heart and how an investigational...
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NCT05390892
PREvention of CardIovascular and DiabEtic KidNey Disease in Type 2 Diabetes
This study is currently enrolling.Associated Conditions: DiabetesResearch Area: Translational ResearchResearch Location: OrlandoStudy Purpose: We are doing PRECIDENTD to learn more about diabetes medications that also reduce the risk of heart and kidney disease in people with type 2 diabetes.
Study Duration: 8 years
Study... -
NCT06217302
Effectiveness and safety of Sotagliflozin in slowing kidney function decline in persons with type 1 diabetes and moderate to severe diabetic kidney disease: The SUGARNSALT Trial
This study is currently enrolling.Associated Conditions: DiabetesResearch Area: Translational ResearchResearch Location: OrlandoStudy Purpose: The purpose of this study is to find out if a drug called sotagliflozin (SOTA) can slow kidney function decline in persons with type 1 diabetes and moderate to severe diabetic kidney...
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NCT07237516
Zymfentra (Infliximab-dyyb) REal World Cohort STudy
This study is currently enrolling.Associated Conditions: IBDResearch Area: Digestive Health and SurgeryResearch Location: Orlando -
NCT07052942
Individualizing Treatment for Asthma in Primary Care (iTREAT-PC)
This study is currently enrolling.Associated Conditions: DiabetesResearch Area: Translational ResearchResearch Location: OrlandoiTREAT Study Purpose: The purpose of this study is to compare the safety and effectiveness of two different ways to treat asthma. The first way is adding inhaled corticosteroids to your rescue... -
NCT06513962
Triptorelin and Protection of Ovarian Reserve in Adolescents and Young Adults with Cancer
This study is currently enrolling.Associated Conditions: Pediatric OncologyResearch Area: Pediatric Research and Clinical TrialsResearch Location: OrlandoThis study is being done to answer the following question: Can we do a study to see if receiving the medication triptorelin during chemotherapy reduces the chances of ovarian damage compared to having... -
NCT06958328
A Phase III Randomized Trial of Dose Escalated Radiation in Locally Advanced Pancreas Cancer (LAPC) Patients
This study is currently enrolling.Associated Conditions: RadiationResearch Area: Clinical Cancer ResearchResearch Location: Porter, Colorado -
NCT07184086
The effect of cagrilintide and semaglutide combination treatment compared to a weight-loss inducing diet on energy metabolism in persons living with obesity: an open-label randomised study
This study is currently enrolling.Associated Conditions: Obesity & MetabolismResearch Area: Translational ResearchResearch Location: OrlandoStudy Purpose: The purpose of this study is to provide insight into the effect of Cagrisema on energy metabolism compared with low energy diet alone.
To be enrolled in this study, you must meet...