Clinical Trials
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NCT05789433
Effects of Aerobic Exercise on Skeletal Muscle Remodeling in Colorectal Cancer
This study is currently enrolling.Associated Conditions: Exercise & BioenergeticsResearch Area: Clinical Cancer ResearchResearch Location: OrlandoRESTORE-The purpose of this research study is to determine how different types of exercise change muscle tissue among people who have been diagnosed with colorectal cancer.
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NCT06006923
Randomized trial of Regorafenib in Combination with Pembrolizumab or Pembrolizumab Monotherapy for Patients with MSI-H Colorectal Cancer
This study is currently enrolling.Associated Conditions: GastrointestinalResearch Area: Clinical Cancer ResearchResearch Location: OrlandoThis is a research study to find out if researchers can lower the chance of your colorectal cancer growing or spreading by using a combination of regorafenib and pembrolizumab compared to...
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A Randomized, Open-label Phase 3 Study of Amivantamab + mFOLFOX6 or FOLFIRI Versus Cetuximab + mFOLFOX6 or FOLFIRI as First-line Treatment in Participants with RAS/RAF Wild-Type Unresectable or Metastatic Left-sided Colorectal Cancer (OrigAMI-2)
This study is currently enrolling.Associated Conditions: GastrointestinalResearch Area: Clinical Cancer ResearchResearch Location: AltamonteThe purpose of this study is to compare the effects of two anticancer drugs (amivantamab and cetuximab) when each is given in combination with standard colorectal cancer (CRC) chemotherapies. to...
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NCT06750094
A Randomized, Open-label Phase 3 Study of Amivantamab + FOLFIRI Versus Cetuximab/Bevacizumab + FOLFIRI in Participants with KRAS/NRAS and BRAF Wild-type Recurrent, Unresectable or Metastatic Colorectal Cancer Who Have Received Prior Chemotherapy
This study is currently enrolling.Associated Conditions: GastrointestinalResearch Area: Clinical Cancer ResearchResearch Location: OrlandoThe purpose of this study is to compare the effects of amivantamab in combination with standard of care chemotherapy (FOLFIRI) against cetuximab or bevacizumab in combination with FOLFIRI in...
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NCT06614192
An Open Label, Randomized, Controlled, Global Phase 3 Study Comparing ABBV-400 Monotherapy to LONSURF (Trifluridine and Tipiracil) plus Bevacizumab in Subjects with c-Met Over-Expressed Refractory Metastatic Colorectal Cancer (AndroMETa-CRC-064)
This study is currently enrolling.Associated Conditions: GastrointestinalResearch Area: Clinical Cancer ResearchResearch Location: OrlandoThe purpose of this study is to determine the recommended ABBV-400 dose when ABBV-400 is given alone (monotherapy) in Stage 1, and to assess if ABBV-400 monotherapy is a safe and effective treatment...