Leading-edge medical care through clinical research.

Getting care at AdventHealth Tampa, formerly Florida Hospital Tampa, means getting access to the latest heart care research studies, procedures, and technologies including access to heart treatment clinical trials that aren’t widely available elsewhere.

Following is a list of active studies in which we are currently enrolling patients. If you would like more information about a trial, please call Call813-615-7527 or visit clinicaltrials.gov.

Active Research Trials


AEGIS II: InvestigatingCSL112 in Subjects with Acute Coronary Syndrome. Lead: Poliana Desarden

APPRAISE ATP: Assessment of primary prevention patients receiving an ICD. Lead: Poliana Desarden

BIOFLOW-VII: Confirming that the clinical performance of the Orsiro stent in a real-world setting is similar to the clinical performance observed for Orsiro in the BIOFLOW-V Investigational Device Exemption pivotal trial. Closed to enrollment. Lead: Juliet Bala

BIO-LIBRA: Analysis of sex- and device-specific factors on outcomes in patients with non-ischemic cardiomyopathy. Lead: Juliet Bala

CLOUT: Evaluate real world patient outcomes after treatment of acute and non-acute lower extremity deep vein thrombosis (DVT) with the ClotTriever Thrombectomy System. Lead: Juliet Bala

DAPA ACT HF-TIMI 68: Dapagliflozin and effect on cardiovascular events in acute heart failure-thrombolysis in myocardial infarction 68. Lead: Heather Davis

FROZEN: To establish the safety and effectiveness of the Boston Scientific Cardiac Cryoablation System for treatment of symptomatic, drug refractory, recurrent, paroxysmal atrial fibrillation. Lead: Cynthia Paysor

KBS Blood Glucose: To collect calibration and performance data of the KBS Systems 1.0 non-invasive glucose monitoring device. Lead: Nyasha McLean

KNOCOUT PE: Ekosonic registry of the treatment and clinical outcomes of pulmonary embolism. Closed to enrollment. Lead: Juliet Bala

PARAGLIDE-HF: Assesses the effect of sacubitril/valsartan vs. valsartan on changes in NT-proBNP and outcomes, safety and tolerability in patients with HFpEF. Lead: Cynthia Paysor


ACTIV4-ACUTE: Compares the effectiveness of antithrombotic strategies for prevention of adverse outcomes in COVID-19 positive inpatients. Lead: Nyasha McLean

ANA001-001: Testing Niclosamide to see how well the drug will help with Covid-19. Lead: Poliana Desarden

PYAB: Testing LY3819253 and LY3832479 in participants with mild to moderate Covid-19 illness of the demographic of 65 and older. Lead: Poliana Desarden

PYAH: Testing LY3819253 and LY3832479 in participants with early symptoms of Covid-19 of the demographic of 18-65. Lead: Poliana Desarden

ReSTEM: Utilizing umbilical cord lining stem cells to treat patients with acute respiratory distress syndrome caused by Covid-19. Lead: Poliana Desarden


ADMIRE-CD-II: Assess efficacy and safety of Adult Allogeneic Expanded Adipose-derived Stem Cells (eASC) for the Treatment of Complex Perianal Fistula(s) in Patients with Crohn's Disease. Lead: Christopher Carr

AURORA: Evaluate the efficacy and safety of Cenicriviroc for treatment of Liver Fibrosis in patients with NASH. Lead: Christopher Carr

Darvadstrocel-3003: Evaluate the long-term safety and efficacy of Darvadstrocel in the Treatment of Complex Perianal Fistula in Subjects with Crohn’s Disease who have participated in ADMIRE-CD-II Study. Lead: Christopher Carr

G1T28: Utilization of trilaciclib to see the possible advantages in protecting the bone marrow and the immune system and improving chemotherapy antitumor efficacy in patients with metastatic triple negative breast cancer. Lead: Christopher Carr

GHPANC-1-001: Determine the maximum tolerated dose and evaluate the efficacy and safety of Antroquinonol in Combination with nab-paclitaxel and gemcitabine in first line Metastatic Pancreatic Cancer. Lead: Christopher Carr

HBOT: Evaluate pre-operative hyperbaric oxygen therapy (HBOT) vs. no therapy to determine if pre-op HBOT can improve post-operative outcomes. Lead: Kaitlyn Crespo

PANC VOL: Study to determine if length of duodenum and volume of pancreas removed can be used as a predictive factor for the development of post-operative diabetes. Lead: Kaitlyn Crespo

PANOVA-3: Evaluate the effect of Tumor Treating Fields (TTFields, 150 kHz) as front line treatment of Locally Advanced Pancreatic Adenocarcinoma concomitant with gemcitabine and nab-paclitaxel. Lead: Christopher Carr

PRESERVE 1: Evaluate Trilaciclib versus Placebo in Patients Receiving FOLFOXIRI/Bevacizumab for Metastatic Colorectal Cancer. Lead: Christopher Carr

TAMLAPS: Registry and tissue sample consent specifically for patients scheduled for the TAMLAPS procedure. Lead: Kaitlyn Crespo

TYME-88: A Multi-Center Study of SM-88 in Subjects with Pancreatic Cancer. Lead: Christopher Carr


AMG-570/SLE: Determine if AMG 570 could be a useful therapeutic agent in the current treatment landscape where subjects with systemic lupus erythematosus (SLE) have ongoing disease activity despite treatment with standard of care therapies. Lead: Gretchen Pifer

B7931028: Assessment of PF-06700841 in participants with moderate to severe active, generalized Systemic Lupus Erythematosus (SLE) that have inadequate response to standard of care. Lead: Dianne Morales

GSK-20190: Efficacy and Safety of GSK3196165 Versus Placebo and Tofacitinib in Participants With Moderately to Severely Active Rheumatoid Arthritis Who Have an Inadequate Response to Methotrexate. Lead: Judy Lara

GSK-20218: Efficacy and Safety of GSK3196165 (Otilimab) Versus Placebo and Sarilumab in Participants With Moderately to Severely Active Rheumatoid Arthritis Who Have an Inadequate Response to Biological Disease-modifying Antirheumatic Drug (DMARDs) and/or Janus Kinase (JAK) Inhibitors. Lead: Judy Lara

PA0010: A Study to Test the Efficacy and Safety of Bimekizumab in the Treatment of Subjects With Active Psoriatic Arthritis (BE OPTIMAL). Lead: Marisabel Collado

PA0011: A Study to Evaluate the Efficacy and Safety of Bimekizumab in the Treatment of Subjects with Active Psoriatic Arthritis (BE COMPLETE). Lead: Marisabel Collado

TV48125: A Study to Test the Effectiveness and Safety of Fremanezumab on Patients With Fibromyalgia. Lead: Marisabel Collado