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Expertise of James Mayo, MD

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James L. Mayo, MD, is a board-certified plastic and reconstructive surgeon, specializing in microsurgery reconstruction of the breast, head and neck, and extremities, as well as general reconstruction. Dr. Mayo received his medical degree from the Medical University of South Carolina. He completed a plastic and reconstructive surgery residency at Louisiana State University followed by a reconstructive microsurgery fellowship at New York University.

With a rich background in complex reconstruction, Dr. Mayo specialized in all types of free flap breast reconstruction, including the abdominally based DIEP flap as well as thigh-based and gluteal free flaps. Dr. Mayo will also selectively combine or stack flaps to provide the optimal volume for an aesthetic reconstruction. While also offering implant-based reconstruction, Dr. Mayo has all of the tools and resources to provide patient-specific breast reconstruction.

Dr. Mayo has worked alongside pioneers in the field of reconstructive microsurgery and is known as an expert in the areas of breast and head and neck reconstruction.

Personal Interests

Family time, cooking, fishing

Care Philosophy

I strive to treat all patients as if they are my own family members. To that end, I make an effort to stay at the forefront of progression within my field of Plastic Surgery while also taking a step back with each patient to view the whole clinic and personal aspects of each patient’s story.

Areas Served
Orlando, FL | New Smyrna Beach, FL
Languages Spoken

Medical University of South Carolina College of Medicine


Plastic Surgery at Louisiana State University School of Medicine in New Orleans

Surgery at Orlando Health


Microsurgery at New York University

Board Certification

Surgery: The American Board of Surgery

Plastic Surgery: American Board of Plastic Surgery

Ages Accepted